研究業績

論文･総説など

• Hydrogen-rich bath with nano-sized bubbles improves antioxidant capacity based on oxygen radical absorbing and inflammation levels in human serum.

  Tanaka Y, Xiao L, Miwa N.
  Med Gas Res. 2022; 12(3):91-99. doi: 10.4103/2045-9912.330692.

  PMID: 34854419
• Enzyme-digested Colla Corii Asini (E'jiao) suppresses lipopolysaccharide-induced inflammatory changes in THP-1 macrophages and OP9 adipocytes.

  Xiao L, Mochizuki M, Fan Y, Nakahara T, Liao F.
  Hum Cell.2022;35(3):885-895. doi: 10.1007/s13577-022-00694-5.

  PMID: 35359251
• Bur1 functions with TORC1 for vacuole-mediated cell cycle progression.

  Jin Y, Jin N, Oikawa Y, Benyair R, Koizumi M, Wilson TE, Ohsumi Y, Weisman LS.
  EMBO Rep. 2022 Apr 5;23(4):e53477. doi: 0.15252/embr.202153477. Epub 2022 Feb 15.

  PMID: 35166010
• Hydrogen-Rich Water Prevents Dehydration-Induced Cellular Oxidative Stress and Cell Death in Human Skin Keratinocytes.

  Xiao L, Miwa N.
  Hydrogen. 2022 Jan; 3(1):62-71.

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• 口腔の加齢変化と健康

  島村直宏，島村結歧乃，肖黎．
  New Food Industry，64（10）：641-644，2022.

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• Nutrient composition and active components of edible bird nest.

  Li Xiao, Dong liang Wang.
  New Food Industry，64（9）：579-582，2022.

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• 液胞による細胞周期制御　　[特集]リソソーム研究の新展開

  神唯
  生体の科学　73(3): 235-240, 2022

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• Characterization of dental pulp stem cells isolated from a patient diagnosed with Crouzon syndrome.

  Torii D, Kobayashi T, Horie T, Tsutsui TW.
  J Cell Physiol. 2021 Jul;236(7):5317-5324.doi: 10.1002/jcp.30241. Epub 2021 Jan 1.

  PMID: 33386632
• Ren Shen Yang Rong Tang and other traditional Chinese medicines exhibit antioxidant and anti-inflammatory capacities and suppress acetylcholinesterase activity in PC12 neuronal cells.

  Xiao L, Liao F, Fan Y, Miwa N.
  Longhua Chin Med 2021; 4:13. doi: 10.21037/lcm-21-12.

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• Hydrogen Nano-Bubble Water Suppresses ROS Generation, Adipogenesis, and Interleukin-6 Secretion in Hydrogen-Peroxide- or PMA-Stimulated Adipocytes and Three-Dimensional Subcutaneous Adipose Equivalents.

  Xiao L, Miwa N.
  Cells. 2021 Mar 11;10(3):626. doi: 10.3390/cells10030626.

  PMID: 33799840
• Hydrogen-Generating Silica Material Prevents UVA-Ray-Induced Cellular Oxidative Stress, Cell Death, Collagen Loss and Melanogenesis in Human Cells and 3D Skin Equivalents.

  Xiao L, Mochizuki M, Nakahara T, Miwa N.
  Antioxidants 2021, 10, 76. Doi:10.3390/antiox10010076.

  PMID: 33430157
• Dental pulp cells of rhesus macaque deciduous tooth spontaneously gained immortalization ability.

  Tsutsui TW, Kobayashi T, Torii D, Miyasaka N, Satomi T, Suzuki J.
  Jpn. J. Tissue Cult. Dent. Res.）30(1):9-18 2021.

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• COVID-19とワクチンのいま

  肖黎, 中原貴, 望月真．
  日本歯科大学 校友会・歯学会会報 47(1) 26-31 2021年8月

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• COVID-19 と戦う利器―エビデンスが語るマスクの有用性Weapons for fighting COVID-19 ----Evidence shows us how useful masks are

  肖　黎.
  New Food Industry，63（1）：69-71，2021.

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• Enzyme-digested Colla Corii Asini (E’jiao) prevents hydrogen peroxide-induced cell death and accelerates amyloid beta clearance in neuronal-like PC12 cells.

  Xiao L, Liao F, Ide R, Horie T, Fan Y, Saiki C, Miwa N.
  Neural Regen Res. 2020;15(12):2270-2277. doi: 10.4103/1673-5374.285000.

  PMID: 32594048
• Enzyme-digested Colla Corii Asini (E'jiao) accelerates wound healing and prevents ultraviolet A-induced collagen synthesis decline and wrinkle formation in three-dimensional skin equivalents.

  Xiao L, Liao F, Fan Y, Miwa N.
  Hum Cell. 2020; 33(4):1056-1067.doi: 10.1007/s13577-020-00405-y. Erratum in: Hum Cell. 2021 Jan;34(1):291.

  PMID: 32761322
• Characterization of proliferation, differentiation potential, and gene expression among clonal cultures of human dental pulp cells.

  Kobayashi T, Torii D, Iwata T, Izumi Y, Nasu M, Tsutsui TW.
  Hum Cell. 2020 Jul;33(3):490-501.doi: 10.1007/s13577-020-00327-9. Epub 2020 Mar 16.

  PMID: 32180208
• Mitotic phosphorylation of the ULK complex regulates cell cycle progression.

  Yamasaki A, Jin Y, Ohsumi Y.
  PLoS Biol. 2020 Jun 9;18(6):e3000718.doi: 10.1371/journal.pbio.3000718. eCollection 2020 Jun.

  PMID: 32516305.
• A New Method for Testing Filtration Efficiency of Mask Materials Under Sneeze-like Pressure.

  Xiao L, Sakagami H, Miwa N.
  In Vivo. 2020;34:1637-1644.doi:10.21873/invivo.11955.

  PMID: 32503823
• ACE2: The key Molecule for Understanding the Pathophysiology of Severe and Critical Conditions of COVID-19: Demon or Angel?.

  Xiao L, Sakagami H, Miwa N.
  Viruses. 2020;12(5):E491. doi:10.3390/v12050491.

  PMID: 32354022
• Dental Pulp Stem Cells: Advances to Applications.

  Tsutsui TW.
  Stem Cells Cloning. 2020 Feb 13;13:33-42. doi: 10.2147/SCCAA.S166759. eCollection 2020.

  PMID: 32104005
• テレワーク時代における免疫力の高め方COVID-19 をやっつける健全な免疫力Healthy immune system: the power to fight COVID-19，

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  New Food Industry，62（10）：707-708，2020.

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• 手作りマスク安全なの？マスク用生地のフィルター性能簡易測定法の開発

  肖　黎
  New Food Industry，62（6）：412-414，2020.

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• コロナストレスと楽しい研究生活，Stress from the new coronal virus and my fun research life，

  肖　黎
  New Food Industry，62（6）：443-444，2020.

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• 新型コロナウイルス感染症に対する最新知見と有効な漢方薬

  肖　黎
  New Food Indust，62（3）：181-184，2020.

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• Oxidative Stress-Tolerant Stem Cells from Human Exfoliated Deciduous Teeth Decrease Hydrogen Peroxide-Induced Damage in Organotypic Brain Slice Cultures from Adult Mice.

  Xiao L, Saiki C, Okamura H.
  Int J Mol Sci. 2019;20 pii: E1858. doi: 10.3390/ijms20081858.

  PMID: 30991705
• Biological effects of traditional Chinese medicine Corii colla asini.

  Xiao L, Liao F, Zhou XS, Qin YF, Miwa N.
  New Food Indust.，61（1）：65-72，2019．

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• 漢方の効能（７）インフルエンザ，漢方薬と腸内細菌叢．

  肖　黎.
  New Food Indust.，61（5）：397-398，2019．

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• Three-Dimensional Inflammatory Human Tissue Equivalents of Gingiva.

  Xiao L, Kumazawa Y, Okamura H.
  J Vis Exp. 2018; 134, doi: 10.3791/57157.

  PMID: 29683455
• CD146 positive human dental pulp stem cells promote regeneration of dentin/pulp-like structures.

  Matsui M, Kobayashi T, Tsutsui TW.
  Hum Cell. 2018 Apr;31(2):127-138. doi: 10.1007/s13577-017-0198-2. Epub 2018 Jan 8.

  PMID: 29313241
• Importance of international communication capability（4）―Health management method in stress society―，

  Sakagami H，Dai Q，Xiao L，Zheng Y, Oishi R，Kanzaki T, Tsuchida Y, Nakai N, Garcia-Contreras R
  New Food Indust 2018 Jun. 60（6）：57-69．

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• Human Dental Pulp Cells Differentiate toward Neuronal Cells and Promote Neuroregeneration in Adult Organotypic Hippocampal Slices In Vitro.

  Xiao L, Ide R, Saiki C, Kumazawa Y, Okamura H.
  Int J Mol Sci. 2017;18: pii: E1745.

  PMID: 28800076
• Early protection to stress mediated by CDK-dependent PI3,5P₂ signaling from the vacuole/lysosome.

  Jin N, Jin Y, Weisman LS.
  J Cell Biol. 2017 Jul 3;216(7):2075-2090. doi: 10.1083/jcb.201611144. Epub 2017 Jun 21.

  PMID: 28637746.
• Cover Image, J Cell Biochem.

  Xiao L, Miwa N.
  Volume 118, Number 2, February 2017 DOI: 10.1002/jcb.25848.

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• Importance of international communication capability (4)―difference in the palatability of Chinese cuisine between Japan and China―.

  Sakagami H, Xiao L, Dai Q, Oishi R, Kanzaki T.
  New Food Indust; 2017 ;59 (6): 71-93.

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• The importance of international communication skills (5) How can we not be left behind in the times.

  Sakagami H, Xiao L, Dai Q, Oishi R, Kanzaki T, Tsuchida Y.
  New Food Indust; 2017 ;59 (11): 69-81.

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• 細胞分裂時における細胞小器官（オルガネラ）の分配機構.

  神　唯、Lois S. Weisman
  化学と生物　55(4): 269-277, 2017

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• Hydrogen-rich water achieves cytoprotection from oxidative stress injury in human gingival fibroblasts in culture or 3D-tissue equivalents, and wound-healing promotion, together with ROS-scavenging and relief from glutathione diminishment.

  Xiao L, Miwa N.
  Hum Cell. 2016 Nov 1. 30 (2), 72-87. DOI 10.1007/s13577-016-0150-x.

  PMID: 27804028
• Bone morphogenetic protein 7 induces cementogenic differentiation of　human periodontal ligament-derived mesenchymal stem cells.

  Torii D, Tsutsui TW, Watanabe N, Konishi K.
  Odontology. 2016 Jan;104(1):1-9. doi: 10.1007/s10266-014-0182-1. Epub 2014 Dec 3.

  PMID: 25464857
• Embryonic tongue morphogenesis in an organ culture model of mouse mandibular arches: blocking Sonic hedgehog signaling leads to microglossia.

  Torii D, Soeno Y, Fujita K, Sato K, Aoba T, Taya Y.
  In Vitro Cell Dev Biol Anim. 2016 Jan;52(1):89-99. doi: 10.1007/s11626-015-9951-6. Epub 2015 Sep 3.

  PMID: 26334330
• The Lipophilic Vitamin C Derivative, 6-O-Palmitoylascorbate Protects Human Keratinocytes and 3D-Human Skin Equivalents Against X-Ray-Induced Oxidative Stress and Apoptosis More Markedly Than L-Ascorbic Acid.

  Xiao L, Miwa N.
  J Cell Biochem. 2017 Feb;118(2):318-329. doi: 10.1002/jcb.25639. Epub 2016 Jul 22.

  PMID: 27350661.
• The vacuole/lysosome is required for cell-cycle progression.

  Jin Y, Weisman LS.
  Elife. 2015 Aug 31;4:e08160. doi: 10.7554/eLife.08160.

  PMID: 26322385.
• Close encounters of the lysosome-peroxisome kind.

  Jin Y, Strunk BS, Weisman LS.
  Cell. 2015 Apr 9;161(2):197-8. doi: 10.1016/j.cell.2015.03.046.

  PMID: 25860602
• Cementogenic potential of multipotential mesenchymal stem cells purified from the human periodontal ligament.

  Torii D, Konishi K, Watanabe N, Goto S, Tsutsui T.
  Odontology. 2015 Jan;103(1):27-35. doi: 10.1007/s10266-013-0145-y. Epub 2014 Jan 8.

  PMID: 24399512
• In vivo stem cell transplantation using reduced cell numbers.

  Tsutsui TW.
  Methods Mol Biol. 2015;1212:201-7. doi: 10.1007/7651_2014_120.

  PMID: 25208754