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School of Life Dentistry at Tokyo



The Graduate School

The Graduate School of Life Dentistry at Tokyo and that at Niigata were established in April 1960 and April 1990, respectively. The schools' objectives are, first, to conduct research on and April 1990 training in dental theory and practice; second, to give students a high degree of expertise to enable them to contribute to advances in dentistry; third, to provide training in a broad spectrum of research fields so students can practice in many places, such as in international research institutions. A unique curriculum has been introduced that is free of preconceived or conventional ideas and integrates both basic studies and clinical practice. New research facilities as well as those for collaborative research are available for the students' use, and many students who complete the graduate course remain at the university for further research while teaching undergraduates.

Major Subject Programs and Themes of Study

The principal research content of the research department at the Nippon Dental University School of Life Dentistry at Tokyo.



Major Subject Programs (Director) Themes of Study
Anatomy
(SATO Iwao)
  1. Anatomical study of temporomandibular joint.
  2. Analysis of vascular factors in maxillofacial region.
  3. Molecular mechanism of maxillofacial development.
Histology
(AIYAMA Shigeo)
  1. Histological and cytological study on development and differentiation of salivary glands.
  2. Histological and cytological study on atrophy and regeneration of salivary glands.
  3. Comparative histology of salivary glands.
Physiology
(MATSUMOTO Shigeji)
  1. The relationship between the movement of various ions and the excitability of dissociated trigeminal ganglion neurons.
  2. The central pathway and descending inhibition of orofacial pain.
  3. Effect of upper airway involved in the orofacial region on respiration.
Biochemistry
  1. Signal transduction and transcriptional regulation in carcinomas.
  2. Mechanism of differentiation and dedifferentiation of kerafinacytes.
  3. Mechanism adapting non-tunorgenic disease development and progression.
Pathology
(AOBA Takaaki)
  1. Elucidation of molecular network governing maxillofacial development and malformation.
  2. Multidimentional analysis of cell-tissue architectures of oral organs and pathologic lesions.
  3. Understanding of function RNA-protein interaction and its significance in pathogenesis.
Microbiology
(KONISHI Seiji)
  1. Genetical and biochemical study of virulence factors in bacteria associated with chronic periodontitis.
  2. Genetical and biochemical study of virulence factors in bacteria associated with aggressive periodontitis.
  3. Molecular biological analysis of pathogenicity of viridans streptococci for infective endo carditis.
Pharmacology
(TSUTSUI Takeki)
  1. Analysis of the protein-nucleic acid interaction in dental pulp activation and tooth regeneration.
  2. Molecular mechanisms of aging and immortalization of human cells.
  3. Assessment of safety of diverse chemicals used in dental practice.
Oral Health
(YAEGAKI Ken)
  1. Carcinogencities and phothogenicities of Oral Malodorous compounds (volatile sulfur compounds).
  2. Children's health behaviors, daily life behaviors and prevention of life-style related disease.
  3. The effects of periodontitis on systematic conditions: studies in stem cells.
Department of Dental Materials Science
(YOSHIDA Takaichi)
  1. Development of Au-Cu-Zn shape memory alloy.
  2. Dental application of function water.
  3. Development of light cure apparatus using blue-light emitting diode.


Major Subject Programs (Director) Themes of Study
Endodontics and Operative Dentistry
(KATSUUMI Ichiro, NARA Yoichiro)
  1. Development on endodontic agents, instruments, devices and materials, and investigation of root canal preparation method and root canal obturation method.
  2. Investigation of inflammatory process of pulp and periapical tissue, mechanism of root resorption, and treatment of endodontic disease.
  3. Investigation of the next-generation restorative materials and basic/clinical examination of bio-conservative dental therapy.
Removable Prosthodontics
(KOBAYASHI Yoshinori, SHIGA Hiroshi)
  1. Mechanism of brain, sleep, and pain, and their relation with occlusion and masticatory function.
  2. Relationship between occlusion and masticatory function.
  3. Establishing a science of dental prosthodontics that conforms to masticatory function.
Crown & Bridge Prosthodontics
(SHINYA Akiyoshi)
  1. Development of computer aided diagnosis system involving realistic models of teeth and oral structures obtained by CT. This system related with finite element analysis and CAD/CAM systems.
  2. Dental adhesives and aesthetic colorations research for teeth, composite, porcelain, zirconium and new materials.
  3. Materials science and clinical evaluation of fibre-reinforced composites in dentistry and orthopedics. We have strong collaboration with world-wide research departments.
Department of Oral and Maxillofacial Surgery
(SATO Tazuko)
  1. Development research of the new regenerative medical materials applied DDS to the chronic osteomylitis in the jaw.
  2. The program of tissue regeneration using growth factors and peptides.
  3. The regenerative medical engineering for bone, periodontal tissue and salivary gland.
Orthodontics
(NAKAHARA Rizako)
  1. Research of the cranicfacial morphology and the dental arch form using two and three-dimensional analysis.
  2. The relationship between masticatory function and malocclusion.
  3. Anthropological research of the cranicfacial morphology and the dental arch form.
Oral and Maxillofacial Radiology
(YOSUE Takashi)
  1. Radiation dosimetry and protection. (Radiation physics)
  2. Bone and soft tissue change due to irradiation. (Radiation biology)
  3. Image diagnosis related to implant dentistry. (Radiographic interpretation)
Pediatric Dentistry
(KARIBE Hiroyuki)
  1. Emotional mechanism in children during dental treatment.
  2. De/remineralization of dental caries in childhood and caries prevention.
  3. Change of dent-maxillo-craniofacial growth in children with systematic disease.
Dental Anesthesiology
(SUNADA Katsuhisa)
  1. The study of anesthetic effect of local anesthetic solutions.
  2. The use of α2 adrenoceptor agonist in dental field.
  3. The study of intravenous sedation for sedative drugs, evaluation and procedure.
Periodontology
(NUMABE Yukihiro)
  1. Growth factor for periodontal tissues.
  2. Smoking and periodontal disease.
  3. Genetic factor for periodontal disease.
  4. Research on New Periodontal Examinations.

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